Publicaciones (desde 1999)

2021

Vicente-Soler, J.; Soto, T.; Franco, A.; Cansado, J.; Madrid, M. The Multiple Functions of Rho GTPases in Fission Yeasts. Cells 2021, 10, 1422. https://doi.org/10.3390/cells10061422

Gómez-Gil, E.; Franco, A.; Vázquez-Marín, B.; Prieto-Ruiz, F.; Pérez-Díaz, A.; Vicente-Soler, J.; Madrid, M.; Soto, T.; Cansado, J. Specific Functional Features of the Cell Integrity MAP Kinase Pathway in the Dimorphic Fission Yeast Schizosaccharomyces japonicus. Journal of Fungi 2021, 7, 482. https://doi.org/10.3390/jof7060482

2020

Gómez-Gil E, Martín-García R, Vicente-Soler J, Franco A, Vázquez-Marín B, Prieto-Ruiz F, Soto T, Pérez P, Madrid M, Cansado J. Stress-activated MAPK signalling controls fission yeast actomyosin ring integrity by modulating formin For3 levels. Elife. 2020. 11;9:e57951. doi: 10.7554/eLife.57951.

Prieto-Ruiz F, Vicente-Soler J, Franco A, Gómez-Gil E, Sánchez-Marinas M, Vázquez-Marín B, Aligué R, Madrid M, Moreno S, Soto T, Cansado J. RNA-Binding Protein Rnc1 Regulates Cell Length at Division and Acute Stress Response in Fission Yeast through Negative Feedback Modulation of the Stress-Activated Mitogen-Activated Protein Kinase Pathway. mBio. 2020. 11(1):e02815-19. doi: 10.1128/mBio.02815-19.

2019

Gómez-Gil E, Franco A, Madrid M, Vázquez-Marín B, Gacto M, Fernández-Breis J, Vicente-Soler J, Soto T, Cansado J. Quorum sensing and stress-activated MAPK signaling repress yeast to hypha transition in the fission yeast Schizosaccharomyces japonicus. PLoS Genet. 2019 15(5):e1008192. doi:10.1371/journal.pgen.1008192.

Pérez P, Soto T, Gómez-Gil E, Cansado J. Functional interaction between Cdc42 and the stress MAPK signaling pathway during the regulation of fission yeast polarized growth. Int Microbiol. 2019. Apr 15. doi: 10.1007/s10123-019-00072-6.

2018

Cansado J. To finish things well: cysteine methylation ensures selective GTPase membrane localization and signalling. Curr Genet. 2018. 64(2):341-344. doi: 10.1007/s00294-017-0756-x.

Pérez P, Cortés JCG, Cansado J, Ribas JC. Fission yeast cell wall biosynthesis and cell integrity signalling. The Cell Surface. 2018. 4:1-9. doi: 10.1016/j.tcsw.2018.10.001

Sanchez-Marinas M, Gimenez-Zaragoza D, Martin-Ramos E, Llanes J, Cansado J, Pujol MJ, Bachs O, Aligue R. Cmk2 kinase is essential for survival in arsenite by modulating translation together with RACK1 orthologue Cpc2 in Schizosaccharomyces pombe.  Free Radic Biol Med. 2018. 129:116-126. doi: 10.1016/j.freeradbiomed.2018.09.024.

2017

Madrid M, Vázquez-Marín B, Soto T, Franco A, Gómez-Gil E, Vicente-Soler J, Gacto, M, Pérez P, Cansado J. Differential functional regulation of PKC orthologs in fission yeast.
J. Biol Chem. 2017. 292(27):11374-11387. doi: 10.1074/jbc.M117.786087.

Franco A, Soto T, Martín-García R, Madrid M, Vázquez-Marín B, Vicente-Soler J, Coll PM, Gacto M, Pérez P, Cansado J.Distinct functional relevance of dynamic GTPase cysteine methylation in fission yeast.
Sci Rep. 2017. 7(1):6057. doi: 10.1038/s41598-017-06053-x.

2016

Madrid M, Vázquez-Marín B, Franco A, Soto T, Vicente-Soler J, Gacto M, Cansado J. Multiple crosstalk between TOR and the cell integrity MAPK signaling pathway in fission yeast.
‎Sci Rep. 2016. 6. Article number: 37515. doi:10.1038/srep37515.

Vicente-Soler J, Madrid M, Franco A, Soto T, Cansado J, Gacto M. Quorum Sensing as Target for Antimicrobial Chemotherapy.
New Weapons to Control Bacterial Growth. Pag 161-84. 2016.
ISBN: 978-3-319-28366-1; ISBN 978-3-319-28368-5 (eBook). doi: 10.1007/978-3-319-28368-5. Ed. Springer-Verlag.

2015

Vázquez B, Soto T, Del Dedo JE, Franco A, Vicente J, Hidalgo E, Gacto M, Cansado J, Madrid M. Distinct biological activity of threonine monophosphorylated MAPK isoforms during the stress response in fission yeast.
Cell Signal. 2015. 27(12):2534-2542. doi: 10.1016/j.cellsig.2015.09.017.

Kabeche R, Madrid M, Cansado J, Moseley JB. Eisosomes Regulate Phosphatidylinositol 4,5-Bisphosphate (PI(4,5)P2) Cortical Clusters and Mitogen-activated Protein (MAP) Kinase Signaling upon Osmotic Stress.
J Biol Chem. 2015. 290(43):25960-25973.

Madrid M, Jiménez R, Sánchez-Mir L, Soto T, Franco A, Vicente-Soler J, Gacto M, Pérez P, Cansado J. Multiple layers of regulation influence cell integrity control by the PKC ortholog Pck2 in fission yeast.
J Cell Sci. 2015. 128(2):266-80. doi: 10.1242/jcs.158295.

2014

Sánchez-Mir L, Franco A, Martín-García R, Madrid M, Vicente-Soler J, Soto T, Gacto M, Pérez P, Cansado J. Rho2 palmitoylation is required for plasma membrane localization and proper signaling to the fission yeast cell integrity mitogen-activated protein kinase pathway.
Mol Cell Biol. 2014. 34(14):2745-59.

Sánchez-Mir L, Soto T, Franco A, Madrid M, Viana RA, Vicente J, Gacto M, Pérez P, Cansado J. Rho1 GTPase and PKC ortholog Pck1 are upstream activators of the cell integrity MAPK pathway in fission yeast.
PLoS One. 2014. 9(1):e88020. doi: 10.1371/journal.pone.0088020.

Sacristán-Reviriego A, Madrid M, Cansado J, Martín H, Molina M. A conserved non-canonical docking mechanism regulates the binding of dual specificity phosphatases to cell integrity mitogen-activated protein kinases (MAPKs) in budding and fission yeasts.
PLoS One. 2014. 9(1):e85390. doi: 10.1371/journal.pone.0085390. 

2013

Gacto M, Madrid M, Franco A, Soto T, Cansado J, Vicente-Soler J. The Cornerstone of Nucleic Acid-Affecting Antibiotics in Bacteria. Antimicrobial Compounds. Current Strategies and New Alternatives. Pag 149-75. 2013.
ISBN: 978-3642-40443-6. doi: 10.1007/978-3-642-40444-3. Ed. Springer.

Grallert A, Chan KY, Alonso-Nuñez ML, Madrid M, Biswas A, Alvarez-Tabarés I, Connolly Y, Tanaka K, Robertson A, Ortiz JM, Smith DL, Hagan IM. Removal of centrosomal PP1 by NIMA kinase unlocks the MPF feedback loop to promote mitotic commitment in S. pombe.
Curr Biol. 2013. 23(3):213-22. doi:10.1016/j.cub.2012.12.039.

Madrid M, Fernández-Zapata J, Sánchez-Mir L, Soto T, Franco A, Vicente-Soler J, Gacto M, Cansado J. Role of the fission yeast cell integrity MAPK pathway in response to glucose limitation.
BMC Microbiol.2013. 13:34. doi: 10.1186/1471-2180-13-34.

Viana RA, Pinar M, Soto T, Coll PM, Cansado J, Pérez P. Negative functional interaction between cell integrity MAPK pathway and Rho1 GTPase in fission yeast.
Genetics. 2013. 195(2):421-32. doi: 10.1534/genetics.113.154807.

Yu ZY, Zhang MT, Wang GY, Xu D, Keifenheim D, Franco A, Cansado J, Masuda H, Rhind N, Wang Y, Jin QW. Fission yeast nucleolar protein Dnt1 regulates G2/M transition and cytokinesis by downregulating Wee1 kinase.
J Cell Sci. 2013.126(Pt 21):4995-5004. doi:10.1242/jcs.132845.

2012

Sánchez-Mir L, Franco A, Madrid M, Vicente-Soler J, Villar-Tajadura MA, Soto T, Pérez P, Gacto M, Cansado J. Biological significance of nuclear localization of mitogen-activated protein kinase Pmk1 in fission yeast.
J Biol Chem. 2012. 287(31):26038-51. doi: 10.1074/jbc.M112.345611.

2011

Miñarro-Gimenez JA, Egaña Aranguren M, Martínez Béjar R, Fernández-Breis JT, Madrid M. Semantic integration of information about orthologs and diseases: the OGO system.
J Biomed Inform. 2011. 44(6):1020-31. doi: 10.1016/j.jbi.2011.08.002.

2010

Cadou A, Couturier A, Le Goff C, Soto T, Miklos I, Sipiczki M, Xie L, Paulson JR, Cansado J, Le Goff X. Kin1 is a plasma membrane-associated kinase that regulates the cell surface in fission yeast.
Mol Microbiol. 2010. 77(5):1186-202. doi: 10.1111/j.1365-2958.2010.07281.x.

Cansado J, Soto T, Gacto M, Pérez P. Rga4, a Rho-GAP from fission yeast: Finding specificity within promiscuity.
Commun Integr Biol. 2010. 3(5):436-9. doi: 10.4161/cib.3.5.12284.

Núñez A, Franco A, Soto T, Vicente J, Gacto M, Cansado J. Fission yeast receptor of activated C kinase (RACK1) ortholog Cpc2 regulates mitotic commitment through Wee1 kinase.
J Biol Chem. 2010. 285(53):41366-73. doi: 10.1074/jbc.M110.173815.

Pérez P, Cansado J. Cell integrity signaling and response to stress in fission yeast.
Curr Protein Pept Sci. 2010. 11(8):680-92. Review.

Soto T, Villar-Tajadura MA, Madrid M, Vicente J, Gacto M, Pérez P, Cansado J. Rga4 modulates the activity of the fission yeast cell integrity MAPK pathway by acting as a Rho2 GTPase-activating protein.
J Biol Chem. 2010. 285(15):11516-25. doi: 10.1074/jbc.M109.071027.

2009

Núñez A, Franco A, Madrid M, Soto T, Vicente J, Gacto M, Cansado J. Role for RACK1 orthologue Cpc2 in the modulation of stress response in fission yeast.
Mol Biol Cell. 2009. 20(18):3996-4009. doi: 10.1091/mbc.E09-05-0388.

Vicente-Soler J, Soto T, Madrid M, Núñez A, Cansado J, Gacto M. Solubilization and characterization of a cell wall-bound trehalase from ascospores of the fission yeast Schizosaccharomyces pombe.
Microbiol Res. 2009.164(3):304-11.

2008

Barba G, Soto T, Madrid M, Núñez A, Vicente J, Gacto M, Cansado J; Yeast Physiology Group. Activation of the cell integrity pathway is channelled through diverse signalling elements in fission yeast.
Cell Signal. 2008. 20(4):748-57. doi: 10.1016/j.cellsig.2007.12.017.

Villar-Tajadura MA, Coll PM, Madrid M, Cansado J, Santos B, Pérez P. Rga2 is a Rho2 GAP that regulates morphogenesis and cell integrity in S. pombe.
Mol Microbiol. 2008. 70(4):867-81. doi: 10.1111/j.1365-2958.2008.06447.x.

2007

Gacto M, Cansado J, Vicente-Soler J, Soto T, Madrid M. Trehalose in yeast performance: Facts and applications. Hot Spots in Applied Microbiology. Pag 51-70. 2007.
ISBN: 81-308-0144-2. Ed. Research Signpost. Kerala, India.

Madrid M, Núñez A, Soto T, Vicente-Soler J, Gacto M, Cansado J. Stress-activated protein kinase-mediated down-regulation of the cell integrity pathway mitogen-activated protein kinase Pmk1p by protein phosphatases.
Mol Biol Cell. 2007 18(11):4405-19.

Soto T, Núñez A, Madrid M, Vicente J, Gacto M, Cansado J. Transduction of centrifugation-induced gravity forces through mitogen-activated protein kinase pathways in the fission yeast Schizosaccharomyces pombe.
Microbiology. 2007. 153(Pt 5):1519-29.

2006

Lapeña MA, Vicente-Soler J, Soto T, Madrid M, Núñez A, García E, Cansado J, Gacto M. Light-induced rhythmic changes in thermotolerance in stationary-phase cells of Candida utilis.
Int Microbiol. 2006. 9(1):61-4.

Madrid M, Soto T, Khong HK, Franco A, Vicente J, Pérez P, Gacto M, Cansado J. Stress-induced response, localization, and regulation of the Pmk1 cell integrity pathway in Schizosaccharomyces pombe.
J Biol Chem. 2006. 281(4):2033-43.

2005

Franco A, Soto T, Madrid M, Vicente-Soler J, Gacto M, Cansado J. Functional characterization of Schizosaccharomyces pombe neutral trehalase altered in phosphorylatable serine residues.
Arch Microbiol. 2005. 183(6):394-400.

2004

Madrid M, Soto T, Franco A, Paredes V, Vicente J, Hidalgo E, Gacto M, Cansado J. A cooperative role for Atf1 and Pap1 in the detoxification of the oxidative stress induced by glucose deprivation in Schizosaccharomyces pombe.
J Biol Chem. 2004. 279(40):41594-602.

Paredes V, Franco A, Madrid M, Soto T, Vicente-Soler J, Gacto M, Cansado J. Transcriptional and post-translational regulation of neutral trehalase in Schizosaccharomyces pombe during thermal stress.
Yeast. 2004. 21(7):593-603.

2003

Franco A, Soto T, Vicente-Soler J, Paredes V, Madrid M, Gacto M, Cansado J. A role for calcium in the regulation of neutral trehalase activity in the fission yeast Schizosaccharomyces pombe.
Biochem J. 2003. 376(Pt 1):209-17.

Gacto M, Soto T, Vicente-Soler J, Villa TG, Cansado J. Learning from yeasts: intracellular sensing of stress conditions.
Int Microbiol. 2003. 6(3):211-9.

Paredes V, Franco A, Soto T, Vicente-Soler J, Gacto M, Cansado J. Different roles for the stress-activated protein kinase pathway in the regulation of trehalose metabolism in Schizosaccharomyces pombe.
Microbiology. 2003. 149(Pt 7):1745-52.

Soto T, Vicente-Soler J, Cansado J, Gacto M. Heat-shock induces activation on trehalase in the yeast Zygosaccharomyces rouxii. Non-Conventional yeasts in Genetics, Biochemistry and Biotecnology. Springer Lab Manual. Vol 67. Pag 423-31. 2003.
ISBN: 3-540-44215-4. Ed. Springer-Verlag. Berlin, Heilderberg, New York.

2002

Soto T, Beltrán FF, Paredes V, Madrid M, Millar JB, Vicente-Soler J, Cansado J, Gacto M. Cold induces stress-activated protein kinase-mediated response in the fission yeast Schizosaccharomyces pombe.
Eur J Biochem. 2002. 269(20):5056-65.

Soto T, Franco A, Padmanabhan S, Vicente-Soler J, Cansado J, Gacto M. Molecular interaction of neutral trehalase with other enzymes of trehalose metabolism in the fission yeast Schizosaccharomyces pombe.
Eur J Biochem. 2002. 269(15):3847-55.

2001

Buck V, Quinn J, Soto Pino T, Martin H, Saldanha J, Makino K, Morgan BA, Millar JB. Peroxide sensors for the fission yeast stress-activated mitogen-activated protein kinase pathway.
Mol Biol Cell. 2001. 12(2):407-19.

Gacto M, Cansado J, Vicente-Soler J, Soto T, Franco A, Paredes V, Beltrán FF. Regulation of trehalase metabolism in fission yeast: genetic and biochemical approaches. Recent Research Developments in Genetics.Vol 1. Pag 23-34. 2001.
ISBN: 81-7736-049-3. Ed. Research Signpost. Kerala, India.

2000

Beltrán FF, Castillo R, Vicente-Soler J, Cansado J, Gacto M. Role for trehalase during germination of spores in the fission yeast Schizosaccharomyces pombe.
FEMS Microbiol Lett. 2000. 193(1):117-21.

Franco A, Soto T, Vicente-Soler J, Guillén PV, Cansado J, Gacto M. Characterization of tpp1(+) as encoding a main trehalose-6P phosphatase in the fission yeast Schizosaccharomyces pombe.
J Bacteriol. 2000. 182(20):5880-4.

Gacto M, Vicente-Soler J, Cansado J, Villa TG. Characterization of an extracellular enzyme system produced by Micromonospora chalcea with lytic activity on yeast cells.
J Appl Microbiol. 2000. 88(6):961-7.

1999

Soto T, Fernández J, Vicente-Soler J, Cansado J, Gacto M. Accumulation of trehalose by overexpression of tps1, coding for trehalose-6-phosphate synthase, causes increased resistance to multiple stresses in the fission yeast Schizosaccharomyces pombe.
Appl Environ Microbiol. 1999. 65(5):2020-4.

Wilkinson MG, Pino TS, Tournier S, Buck V, Martin H, Christiansen J, Wilkinson DG, Millar JB. Sin1: an evolutionarily conserved component of the eukaryotic SAPK pathway.
EMBO J. 1999. 18(15):4210-21.