Dr. José Ruiz

Department of Inorganic Chemistry - Murcia University

 

 

Spanish version spain

Member of the Working Group #4 of COST Action CM1105 (“Functional metal complexes that bind to biomolecules”)

Present position
José Ruiz is Professor in Inorganic Chemistry
Faculty: Chemistry
Department: Inorganic Chemistry. Metallopharmaceutical Group.
Postal address: Departamento de Química Inorgánica, Universidad de Murcia, Campus Universitario de Espinardo, 30071 – Espinardo - Murcia. Spain
Phone: +34 868 88 74 55 / Fax: +34 868 88 41 48
e-mail: jruiz@um.es

Postdoctoral experience

Center: Department of Chemistry. University of Sheffield. U.K.
Date: 1984 / 86


Last publications

A photoactivated Ir(iii) complex targets cancer stem cells and induces secretion of damage-associated molecular patterns in melanoma cells characteristic of immunogenic cell death. Gloria Vigueras, Lenka Markova, Vojtech Novohradsky, Alicia Marco, Natalia Cutillas, Hana Kostrhunova, Jana Kasparkova, José Ruiz and Viktor Brabec. Inorg. Chem. Front. (2021) Advance Article. DOI: https://doi.org/10.1039/D1QI00856K

 

Targeting translation: a promising strategy for anticancer metallodrugs. EnriqueOrtega, GloriaVigueras, Francisco José Ballester and JoséRuiz. Coordination Chemistry Reviews, 446, 214129 (2021) . DOI: 10.1016/j.ccr.2021.214129

 

A 2-(benzothiazol-2-yl)-phenolato platinum(II) complex as potential photosensitizer for combating bacterial infections in lung cancer chemotherapy. Enrique Ortega, Cristina Pérez-Arnaiz, Venancio Rodríguez, Christoph Janiak, Natalia Busto, Begoña García and José Ruiz. European Journal of Medicinal Chemistry, 222, 113600 (2021). DOI: 10.1016/j.ejmech.2021.113600

 

A Cyclometalated Ir(III) Complex Conjugated to a Coumarin Derivative Is a Potent Photodynamic Agent against Prostate Differentiated and Tumorigenic Cancer Stem Cells. Dr. Vojtech Novohradsky, Dr. Lenka Markova, Dr. Hana Kostrhunova, Prof.Dr. Jana Kasparkova, Prof. José Ruiz, Prof. Vicente Marchán, Prof.Dr. Viktor Brabec. Chemistry – A European Journal, 27, 33, 8547-8556 (2021). DOI: 10.1002/chem.202100568

 

Organoplatinum(II) Complexes Self-Assemble and Recognize AT-Rich Duplex DNA Sequences. Ana Zamora, Erin Wachter, María Vera, David K. Heidary, Venancio Rodríguez, Enrique Ortega, Vanesa Fernández-Espín, Christoph Janiak, Edith C. Glazer, Giampaolo Barone and José Ruiz. Inorg. Chem. 60, 4, 2178–2187 (2021). DOI: 10.1021/acs.inorgchem.0c02648

 

Novel organo-osmium(ii) proteosynthesis inhibitors active against human ovarian cancer cells reduce gonad tumor growth in Caenorhabditis elegans. Enrique Ortega, Francisco J. Ballester, Alba Hernández-García, Samanta Hernández-García, M. Alejandra Guerrero-Rubio, Delia Bautista, M. Dolores Santana, Fernando Gandía-Herrero and José Ruiz. Inorg. Chem. Front., 2021,8, 141-155. DOI: 10.1039/C9QI01704F

 

TAn Erlotinib gold(I) conjugate for combating triple-negative breast cancer. Enrique Ortega, Ana Zamora, Uttara Basu, Petra Lippmann, Venancio Rodríguez, Christoph Janiak, Ingo Ott, José Ruiz. Journal of Inorganic Biochemistry 203 (2020) 110910. DOI: 10.1016/j.jinorgbio.2019.110910

 

Ru(II) photosensitizers competent for hypoxic cancers via green light activation. Francisco J. Ballester, Enrique Ortega, Delia Bautista, M. Dolores Santana and José Ruiz. Coord. Chem. Commun., 2020, 56, 10301. DOI: 10.1039/d0cc02417a

 

Amino-Functionalized Mesoporous Silica Nanoparticle- Encapsulated Octahedral Organoruthenium Complex as an Efficient Platform for Combatting Cancer. Marina Martínez-Carmona,Quy P. Ho, Je´re´my Morand, Ana García, Enrique Ortega, Luiza C. S. Erthal, Eduardo Ruiz-Hernandez, M. Dolores Santana, Jose´ Ruiz,Maria Vallet-Regí,and Yurii K. Gun’ko. Inorg. Chem. 2020, 59, 10275-10284. DOI: 10.1021/acs.inorgchem.0c01436

 

 

 

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