José Ruiz López

Departamento de Química Inorgánica - Universidad de Murcia

 

 

English version unitedkingdom

Bienvenido a la página web de José Ruiz, Catedrático de Química Inorgánica de la Universidad de Murcia.
Miembro del "Working Group #4 of COST Action CM1105” (“Functional metal complexes that bind to biomolecules”)

Datos de interés
Facultad: Química
Departamento: Química Inorgánica. Grupo de Metalofármacos.
Dirección postal: Departamento de Química Inorgánica, Universidad de Murcia, Campus Universitario de Espinardo, 30071 – Espinardo - Murcia
Teléfono: 868 88 74 55 / Fax: 868 88 41 48
Correo electrónico: jruiz@um.es

 

Estancia posdoctoral
Centro: Department of Chemistry. University of Sheffield
Localidad: Sheffield
País: Reino Unido
Fecha: 1984 / 86
Tema: Síntesis y reactividad de pentametilciclopentadienil complejos de rodio e iridio.

   

Últimos artículos

Ruthenium-containing P450 inhibitors for dual enzyme inhibition and DNA damage. Ana Zamora, Catherine A. Denning, David K. Heidary, Erin Wachter, Leona A. Nease, José Ruiz and Edith C. Glazer. Dalton Trans. 2017, 46, 2165-2173. DOI: 10.1039/C6DT04405K

 

Geometry matters: inverse cytotoxic relationship for cis/trans-Ru(ii) polypyridyl complexes from cis/trans-[PtCl2(NH3)2]. E. Wachter, A. Zamora, L. Nease, D. K. Heidary, J. Ruiz and E. C. Glazer, Chem. Comm., 2016, 52, 10121-10124. DOI: 10.1039/c6cc04813g

 

Highly potent extranuclear-targeted luminescent iridium(iii) antitumor agents containing benzimidazole-based ligands with a handle for functionalization. J. Yellol, S. A. Pérez, G. Yellol, J. Zajac, A. Donaire, G. Vigueras, V. Novohradsky, C. Janiak, V. Brabec, J. Ruiz, Chem. Commun., 2016, 52, 14165 - 14168. DOI: 10.1039/c6cc07909a

 

Novel C,N-Cyclometalated Benzimidazole Ruthenium(II) and Iridium(III) Complexes as Antitumor and Antiangiogenic Agents: A Structure-Activity Relationship Study. Yellol J, Pérez SA, Buceta A, Yellol G, Donaire A, Szumlas P, Bednarski PJ, Makhloufi G, Janiak C, Espinosa A, Ruiz J. J Med Chem. 2015, 58, 7310-7327. doi: 10.1021/acs.jmedchem.5b01194.

 

In Vitro Characterization of a Novel C,N-cyclometalated Benzimidazole Ru(II) Arene Complex: Stability, Intracellular Distribution and Binding, Effect on Organic Osmolyte Homeostasis and Induction of Apoptosis. Celina Støving Dam, Sergio Alejo Perez Henarejos, Theodosia Tsolakou, Christian Alexander Segato, Bente Gammelgaard, Gorakh S. Yellol, José Ruiz, Ian Henry Lambert, Stefan Stürup. Metallomics, 2015, Vol. 7, 885-895. DOI: 10.1039/c5mt00056d

 

 

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