Fisiología de la Reproducción  Universidad de Murcia Departamento de Fisiología Facultad de Veterinaria Campus Universitario de Espinardo. 30100 Murcia. España

2015

• ALMELA L, RUIZ S, POTO A, PEINADO B. Comparative study of in vitro fertility of the Murciano-Levantino bull semen after two different sperm refreezing processes. Turkish Journal of Veterinary & Animal Sciences (aceptado, 2015).
• GARCÍA-VÁZQUEZ FA, HERNÁNDEZ-CARAVACA I, YÁNEZ-QUINTANA W, MATÁS C, SORIANO-ÚBEDA C, IZQUIERDO-RICO MJ. Morphometry of boar sperm head and flagellum in semen backflow after insemination. Theriogenology. 2015. http://dx.doi.org/10.1016/j.theriogenology.2015.04.011
• GARCÍA-VÁZQUEZ FA, HERNÁNDEZ-CARAVACA I, MATÁS C, SORIANO-ÚBEDA C, ABRIL-SÁNCHEZ S, IZQUIERDO-RICO MJ. Morphological study of boar sperm during their passage through the female genital tract. Journal of Reproduction and Development.
• HUNTER RHF, GADEA J. Outstanding questions concerning sperm-epithelial binding in the mammalian oviduct. Zygote. ZYG-2014-0113.
• GARDON JC, ESCRIBANO E, ASTIZ S, RUIZ S. Synchronization protocols in Spanish Merino sheep: reduction in time to estrus by the addition of eCG to a progesterone-based estrus synchronization protocol. Annals of Animal Science. 2015. 15 (2): 409-418. DOI: 10.1515/aoas-2015-0003
• GÓMEZ-MARTÍN A, UC N, VIEIRA LA, GADEA J, CÁDENAS J, SÁNCHEZ A, DE LA FE C. Survival capacity of Mycoplasma agalactiae and Mycoplasma mycoides subsp. capri in the diluted semen of goat bucks and their effects on sperm quality. Theriogenology. 2015. 83. 919-919. doi: 10.1016/j.theriogenology.2014.11.029.
• HERNÁNDEZ-CARAVACA I, SORIANO-ÚBEDA C, MATÁS C, IZQUIERDO-RICO MJ, GARCÍA-VÁZQUEZ FA. Boar sperm with defective motility are discriminated in the backflow moments after insemination. Theriogenology. 2015. 83: 655-661. doi: 10.1016/j.theriogenology.2014.10.032.
• LOPEZ-UBEDA R, GARCÍA-VÁZQUEZ FA, ROMAR R, GADEA J, MUÑOZ M, HUNTER RHF, COY P. Oviductal Transcriptome Is Modified after Insemination during Spontaneous Ovulation in the Sow. PLoS One. 2015 Jun 22;10(6):e0130128. doi: 10.1371/journal.pone.0130128. eCollection 2015.
• NAVARRETE FA, GARCÍA-VÁZQUEZ FA, ALVAU A, ESCOFFIER J, KRAPF D, SANCHEZ C, SALICIONI AM, DARSZON A, VISCONTI PE. Biphasic Role of Calcium in Mouse Sperm Capacitation Signaling Pathways. Journal of Cell Physiology. 2015. DOI: 10.1002/jcp.24873
• ROMERO-AGUIRREGOMEZCORTA J, MATÁS C, COY P. α-L-fucosidase enhances capacitation-associated events in porcine spermatozoa. The Veterinary Journal. 2015. 203:109-114. doi: 10.1016/j.tvjl.2014.11.006.
• STETSON I, AVILÉS M, MOROS C, GARCÍA-VÁZQUEZ FA, GIMENO L, ALIAGA C, BALLESTA J, IZQUIERDO-RICO MJ. Four glycoproteins are expressed in the cat zona pellucida. Theriogenology 2015. doi:10.1016/j.theriogenology.2014.12.019
• BALLESTER L, ROMERO-AGUIRREGOMEZCORTA J, SORIANO-ÚBEDA C, MATÁS C, ROMAR R, COY P. Timing of oviductal fluid collection, steroid concentrations and sperm preservation method affect in vitro fertilization efficiency. Fertil Steril. 2014. 102(6): 1762-1768.e1. doi: 10.1016/j.fertnstert.2014.08.009.

2014

• BALLESTER L, ROMERO-AGUIRREGOMEZCORTA J, SORIANO-ÚBEDA C, MATÁS C, ROMAR R, COY P. Timing of oviductal fluid collection, steroid concentrations and sperm preservation method affect in vitro fertilization efficiency. Fertil Steril. 2014. 102(6): 1762-1768.e1. doi: 10.1016/j.fertnstert.2014.08.009.
• HUNTER RHF, GADEA J. Cross-talk between free and bound spermatozoa to modulate initial sperm: egg ratios at the site of fertilisation in the mammalian oviduct. Theriogenology 2014, 82:367-372. DOI:10.1016/j.theriogenology.2014.04.015
• ROMERO-AGUIRREGOMEZCORTA J, SANTA AP, GARCÍA-VÁZQUEZ FA, COY P, MATÁS C. Nitric oxide synthase (NOS) inhibition during porcine in vitro maturation modifies oocyte protein S-nitrosylation and in vitro fertilization. PLoS ONE 2014. 9(12): e115044. doi:10.1371/journal.pone.0115044
  1. SAAVEDRA MD, MONDÉJAR I, COY P, BETANCOURT M, GONZÁLEZ-MÁRQUEZ H, JIMÉNEZ-MOVILLA M, AVILÉS M, ROMAR R. Calreticulin from suboolemmal vesicles affects membrane regulation of polyspermy. Reproduction 2014, 147 (3): 369–378. doi:10.1530/REP-13-0454. ISSN 1470-1626.

2013

• CEBRIÁN-SERRANO A, SALVADOR I, GARCIA-ROSELLÓ E, PERICUESTA E, PÉREZ-CEREZALES S, GUTIERREZ-ADÁN A, COY P, SILVESTRE MA. Influence of oviductal fluid on in vitro fertilisation, development and gene expression of in vitro produced bovine blastocysts.Reproduction in Domestic Animals 2013 Apr;48(2):331-338. doi: 10.1111/j.1439-0531.2012.02157.x.
• CEBRIAN-SERRANO A, SILVESTRE MA, RUIZ S, RATH D. Effect of sex-sorted sperm on development and quality of in vitro-produced bovine embryos derived from ovum pick up oocytes. Animal Science Papers and Reports 2013 31:111-122.
• GADEA J, GUMBAO D, GÓMEZ-GIMENEZ B, GARDÓN JC. Supplementation of the dilution medium with reduced glutathione improves function of frozen-thawed goat spermatozoa. Reproductive Biology 2013. 13:24-33 DOI: 10.1016/j.repbio.2013.01.174
• GRULLÓN LA, GADEA J, MONDÉJAR I, MATÁS C, ROMAR R, COY P. How is plasminogen/plasmin system contributing to regulate sperm entry into the oocyte? Reproductive Sciences Reprod Sci. 2013 Sep;20(9):1075-82. doi: 10.1177/1933719112473657.
• KOHATA C, IZQUIERDO-RICO MJ, ROMAR R, FUNAHASHI H. Development competence and relative transcript abundance of oocytes derived from small and medium follicles of prepubertal gilts. Theriogenology 2013;80: 970-978.
• LUÑO V, LÓPEZ-ÚBEDA R, GARCÍA-VÁZQUEZ FA, GIL L, MATÁS C.Boar sperm tyrosine phosphorylation patterns in the presence of oviductal epithelial cells: in vitro, ex vivo, and in vivo models.Reproduction. 2013 Aug 12;146(4):315-24. doi: 10.1530/REP-13-0159.
• MARTINEZ-SOTO JC, LANDERAS J, GADEA J. Sperm and seminal plasma fatty acids as predictors of cryopreservation success. Andrology 2013 May;1(3):365-75. doi: 10.1111/j.2047-2927.2012.00040.x.
• MONDÉJAR I, AVILÉS M, COY P. The human is an exception to the evolutionarily-conserved phenomenon of pre-fertilization zona pellucida resistance to proteolysis induced by oviductal fluid. Human Reproduction 2013 Mar;28(3):718-28. doi: 10.1093/humrep/des423
• MONDÉJAR I, MARTÍNEZ-MARTINEZ I, AVILÉS M, COY P. Identification of Potential Oviductal Factors Responsible of the Zona Pellucida Hardening and Monospermy During Fertilization in Mammals. Biol Reprod. 2013 Sep 27;89(3):67.doi: 10.1095/biolreprod.113.111385
• OBERLENDER G, SOLIS MURGAS LD, ZANGERONIMO MG, CRISTINA DA SILVA A, DE ALCANTARA MENEZES T, PONTELO TP, VIEIRA LA. Role of insulin-like growth factor-I and follicular fluid from ovarian follicles with different diameters on porcine oocyte maturation and fertilization in vitro. Theriogenology. 2013 Sep 1;80(4):319-27. doi: 10.1016/j.theriogenology.2013.04.018. Epub 2013 May 16.
• RUIZ S, ROMERO-AGUIRREGOMEZCORTA J, ASTIZ S, PEINADO B, ALMELA L, POTO A. Application of reproductive biotechnology for the recovery of endangered breeds: Birth of the first calf of Murciana-Levantina bovine breed derived by OPU, in vitro production and embryo vitrification. Reproduction in Domestic Animals 2013 Dec;48(6):e81-4. doi: 10.1111/rda.12179.
• TUMOVÁ L, ROMAR R, PETR J, SEDMÍKOVÁ M. The effect of protein kinase C activator and nitric oxide donor on oocyte activation and cortical granule exocytosis in porcine eggs. Animal 2013; 7(2):279-286. doi: 10.1017/S1751731112001127
• VIEIRA LA, GADEA J, GARCÍA-VÁZQUEZ FA, AVILÉS-LÓPEZ K, MATÁS C. Equine spermatozoa recovered from epididymides stored at 4ºC for up to 96 h can be successfully cryopreserved. Animal Reproduction Science 2013 Jan 30;136(4):280-8. doi: 10.1016/j.anireprosci.2012.10.027

• COY P, GARCÍA-VAZQUEZ FA, VISCONTI P, AVILES M. Roles of the oviduct in mammalian fertilization. Reproduction (2012) 144 649–660. doi: 10.1530/REP-12-0279
• COY P, JIMÉNEZ-MOVILLA M, GARCÍA-VÁZQUEZ FA, MONDÉJAR I, GRULLÓN L, ROMAR R. Oocytes use plasminogen-plasmin system to remove supernumerary spermatozoa.Human Reproduction 2012 Jul;27(7):1985-93
• HERNÁNDEZ-CARAVACA I, IZQUIERDO-RICO MJ, MATÁS C, CARVAJAL JA, VIEIRA L, ABRIL D, SORIANO-ÚBEDA C, GARCÍA–VÁZQUEZ FA. Reproductive performance and backflow study in cervical and post-cervical artificial insemination in sows. Anim Reprod Sci. 2012 Dec;136(1-2):14-22.
• MONDÉJAR I, ACUÑA S, IZQUIERDO RICO MJ, COY P, AVILÉS M. The oviduct: functional genomic and proteomic approach. Reproduction in Domestic Animals 2012 Jun;47 Suppl 3:22-9.
• MONDÉJAR I, GRULLÓN LA, GARCÍA-VÁZQUEZ FA, ROMAR R, COY P. Fertilization outcome could be regulated by binding of oviductal plasminogen to oocytes and by releasing of plasminogen-activators during interplay between gametes. Fertility and Sterility. 2012 Feb;97(2):453-461.
• ROMAR R, COY P, RATH D. Maturation conditions and boar affect timing of cortical reaction in porcine oocytes. Theriogenology. 2012 Sep 15;78(5):1126-1139.e1. Epub 2012 Jul 3.

2011

• GADEA J, MOLLA M, SELLES E, MARCO MA, GARCIA-VAZQUEZ FA, GARDON JC. Reduced glutathione content in human sperm is decreased after cryopreservation. Effect of the addition of reduced glutathione to the freezing and thawing extenders. Cryobiology. 2011. 62:40-46.
• GARCÍA-VÁZQUEZ FA, HERNÁNDEZ-CARAVACA I, MARTÍN M, GÓMEZ E, RODRÍGUEZ A, SÁNCHEZ-SÁNCHEZ R, GADEA J. Two cases of reciprocal chromosomal translocation (2q-; 8q+) (7q-; 4p+) in piglets produced by ICSI. Reproduction in Domestic Animals. 2011 Aug;46(4):728-30
• GARCÍA-VAZQUEZ FA, GUMBAO D, GADEA J. Inmunolocalización del ADN exógeno en espermatozoides porcinos sometidos a diferentes tratamientos. Revista científica de la Facultad de Ciencias Veterinarias de la Universidad del Zulia.  2011. 21:50-56.
• GARCÍA-VAZQUEZ FA, RUIZ S, GRULLÓN LA, DE ONDIZ A, GUTIERREZ-ADAN A, GADEA J. Factors affecting the sperm mediated gene transfer in porcine. Research in Veterinary Science. 91 (2011) 446–453
• HUNTER RHF, COY P, GADEA J, RATH D. Consideration of viscosity in the preliminaries to mammalian fertilisation. Journal of Assisted Reproduction and Genetics. J Assist Reprod Genet.2011 Mar;28(3):191-7.
• KASHIR J, HEYNEN A, JONES C, DURRANS C, CRAIG J,  GADEA J, TURNER K, PARRINGTON J, COWARD K. Effects of cryopreservation and density gradient washing on phospholipase C zeta (PLC ) concentrations in human sperm. Reprod Biomed Online. 2011 .2011 Aug;23(2):263-7
• MARTINEZ-SOTO JC, GARCÍA-VAZQUEZ FA, GUMBAO D,LANDERAS JL, GADEA J. Assessment of two thawing process of cryopreserved human sperm in pellets. Cryobiology.  2011. 63:131-136.
• MATÁS C. VIEIRA L, GARCÍA-VÁZQUEZ FA, AVILÉS-LÓPEZ K, LOPEZ-UBEDA R, CARVAJAL JA, GADEA J. Effects of centrifugation through three different discontinuous Percoll gradients on boar sperm function. Animal Reproduction Science. 2011. 127(1-2):62-72
• PARRINGTON J, COWARD K, GADEA J. Sperm and Testis Mediated DNA Transfer as a Means of Gene Therapy. Systems Biology in Reproductive Medicine 2011 Feb.;57(1-2):35-42.
• ROMAR R, DE SANTIS T, PAPILLIER P, PERREAU C, THELIE A, DELL’AQUILA ME, MERMILLOD P, DALBIES-TRAN R. Expression of Maternal Transcripts During Bovine Oocyte In Vitro Maturation is Affected by Donor Age. Reproduction in Domestic Animals.  46, e23–e30 (2011)

2010

• AVILES M, GUTIERREZ-ADAN A, COY P. Oviductal secretions: Will they be key factors for the future ARTs?. Molecular Human Reproduction. 2010 16 (12): 896-906.
• CANOVAS S, GUTIERREZ-ADAN A, GADEA J. Effect of exogenous DNA on bovine sperm functionality using Sperm mediated gene transfer (SMGT) technique. Molecular, Reproduction and Development. 2010 Aug;77(8):687-98.
• COY P, AVILES M. What controls polyspermy in mammals, the oviduct or the oocyte? Biol Rev Camb Philos Soc. 2010 Aug;85(3):593-605.
• COY P, LLOYD R, ROMAR R, SATAKE N, MATAS C, GADEA J, HOLT WV. Effects of porcine pre-ovulatory oviductal fluid on boar sperm function. Theriogenology. 2010 Sep 1;74(4):632-42.
• GADEA J, GARCÍA-VAZQUEZ FA. Aplicaciones de los cerdos transgénicos en biomedicina y producción animal. ITEA INFORMACION TECNICA ECONOMICA AGRARIA. 2010. 106(1):15-30.
• GADEA J, GARCÍA-VAZQUEZ FA. Métodos de generación de cerdos transgénicos. ITEA INFORMACION TECNICA ECONOMICA AGRARIA. 2010. 106(1):31-45.
• GARCÍA-VAZQUEZ FA, RUIZ S, GRULLÓN LA, DE ONDIZ A, GUTIERREZ-ADAN A, GADEA J. Transgénesis mediada por espermatozoides en la especie porcina: efecto de la presencia de ADN exógeno sobre la calidad seminal y evaluacion de la producción in vivo de embriones transgénicos. Revista científica de la Facultad de Ciencias Veterinarias de la Universidad del Zulia. 2010. 20:81-88.
• GARCÍA-VAZQUEZ FA, RUIZ S, MATAS C, IZQUIERDO-RICO MJ, GRULLÓN LA, DE ONDIZ A, AVILES-LOPEZ K, VIEIRA L, GUTIERREZ-ADAN A, GADEA J. Efficient Production of Transgenic Piglets using ICSI-SMGT in Combination with Recombinase RecA. Reproduction. 2010 Aug;140(2):259-72.
• MATAS C, SANSEGUNDO M, RUIZ S, GARCIA-VAZQUEZ FA, GADEA J, ROMAR R, COY P. Sperm treatment affects capacitation parameters and penetration ability of ejaculated and epididymal boar spermatozoa. Theriogenology. 2010 Nov;74(8):1327-40.
• MARTINEZ-SOTO JC, HOURCADE JD, GUTIÉRREZ-ADÁN A, LANDERAS JL, GADEA J Effect of genistein supplementation of thawing medium on characteristics of frozen human spermatozoa. Asian Journal of Andrology. 2010 May;12(3):431-41.

2009

• CANOVAS S, ROMAR R, GRULLON LA, AVILES M, COY P. Pre-fertilization zona pellucida hardening by different cross-linkers affects in vitro fertilization in pigs and cattle and improves embryo production in pigs. Reproduction. 2009 May;137(5):803-12
• COY P, GADEA J, RATH D, HUNTER RHF. Differing sperm ability to penetrate the oocyte in vivo and in vitro as revealed using colloidal preparations. Theriogenology. 72 (2009) 1171–1179.
• GARCÍA-ROSELLÓ E, GARCÍA-MENGUAL E, COY P, ALFONSO J, SILVESTRE MA. Intracytoplasmic Sperm Injection in Livestock Species: An Update. Reprod. Domest. Anim. 2009. 44, 143–151.
• GARCÍA-VAZQUEZ FA, GUTIERREZ-ADAN A, GADEA J. Evaluación de la unión espermatozoide-ADN exógeno en espermatozoides eyaculados y epididimarios. Archivos de Medicina Veterinaria. 2009. 41.131-138.
• GARCÍA-VAZQUEZ FA, GARCIA-ROSELLÓ E, GUTIERREZ-ADAN A, GADEA J. Effect of the sperm treatment on efficiency of porcine transgenic embryo production by ICSI-SMGT. Theriogenology. 2009 Sep 1;72(4):506-18. .
• LLOYD RE, ROMAR R, MATAS C, GUTIÉRREZ-ADÁN A, HOLT WV, COY P. Effects of oviductal fluid on the development, quality and gene expression of porcine blastocyst produced in vitro. Reproduction. 2009 Apr;137(4):679-87.