Validation of an innovative method; based on tilt sensing; for the assessment of activity and body position. Bonmatí-Carrión MA, Middleton B, Skene D, Rol MA, Madrid JA. Chronobiology International. 32(5):701-710. Abstract

Ontogeny and aging of the distal skin temperature rhythm in humans. Batinga H, Martinez-Nicolas A, Zorzona-Moreno M, Sanchez-Solis M, Larqué E, Mondéjar MT, Moreno-Casbas M, García FJ, Campos M, Rol MA, Madrid JA. Age. 37(2) doi:10.1007/s11357-015-9768-y. Abstract

Daytime variation in ambient temperatures and blood pressure: Ambulatory winter/summer comparison in healhty young women. Martinez-Nicolas A, Meyer M, Hunkler S, Madrid JA, Rol MA, Meyer AH, Schötzau A, Orgül S, Kräuchi K. Physiology & Behavior. 149(2):203-211. Abstract

Disruption of circadian rhythms and delirium; sleep impairment and sepsis in critically ill patients. Potential therapeutic implications for increased light-dark contrast and melatonin therapy in an ICU environment. Madrid-Navarro CJ, Sanchez-Galvez RM, Martinez-Nicolas A, Marina R, Garcia JA, Madrid JA, Rol MA. Current Pharmaceutical Design. 21(24):3453-3468. Abstract

Circadian activity rhythms during the last days of Nothobranchius rachovii’s life: A descriptive model of circadian system breakdown. Lucas-Sánchez A, Martinez-Nicolas A, Madrid JA, Almaida-Pagan PF, Mendiola P, de Costa J. Chronobiology International. 32:395-404. 2015. Abstract



Protecting the melatonin rhythm through circadian healthy light exposure. Bonmati-Carrion MA, Argüelles R, Martinez-Madrid MJ, Reiter RJ, Hardeland R, Rol MA, Madrid JA. International Journal of Molecular Sciences15(12):23448-23500. 2014. Abstract

Age-related changes in mitochondrial membrane composition of  Nothobranchius rachovii. Lucas-Sánchez A, Almaida-Pagán PF, Tocher DR, Mendiola P, de Costa J. Journals of Gerontology Series A – Biological Sciences and Medical Sciences. 69(2):142-151. 2014. Abstract

The circadian rest-activity rhythm; a potential safety pharmacology endpoint of cancer chemotherapy. Ortiz-Tudela E, Lurisci I, Beau J, Karaboue A, Moreau T, Rol MA, Madrid JA, Lévi F, Innominato PF. International Journal of Cancer. 134(11):2717-2725. Abstract

The characterization of biologial rhythms in mild cognitive impairment. Ortiz-Tudela E, Martinez-Nicolas A, Diaz-Mardomingo C, García-Herranz S, Pereda-Perez I, Valencia A, Peraita H, Venero C, Madrid JA, Rol MA. BioMed Research International. Abstract

Circadian rhythmicity as a predictor of weight-loss effectiveness. Bandin C, Martinez-Nicolas A, Ordovas JM, Madrid JA, Garaulet M. International Journal of Obesity. 38(8):1083-1088. 2014. Abstract

Ambulatory circadian  monitoring (ACM) based on thermometry, motor activity and  body position (TAP): a comparison with polysomnography. Ortiz-Tudela E, Martinez-Nicolas A, Albares J, Segarra F, Campos M, Estivill E, Rol de Lama MA, Madrid JA. Physiology & Behavior. 126:30-38. 2014. Abstract

Circadian phase assessment by ambulatory monitoring in humans: correlation with dim light melatonin onset. Bonmati-Carrion MA, Middleton B, Revell V, Skene D, Rol de Lama MA, Madrid JA. Chronobiology International. 31:137-151. 2014. Abstract

Day-night contrast as source of health for the human circadian system. Martinez-Nicolas A, Madrid JA, Rol de Lama MA. Chronobiology International. 31(3):382-393. 2014. Abstract

Evening physiocal activity alters wrist temperature circadian rhythmicity. Rubio-Sastre P, Gomez-Abellán P, Martínez-Nicolás A, Ordovás JM, Madrid JA, Garaulet M. Chronobiology International. 31(2):276-282. 2014. Abstract

Sleepiness in spanish nursing staff – Influence of chronotype and care unit in circadian rhtyhm impairment: research protocol. Moreno-Casbas T, Ruzafa-Martinez M, Rol de Lama MA, Madrid JA, Serrano-Pinto A, Gonzalez-Maria E, Fuentelsanz-Gallego C.  Journal of Advanced Nursing. 1442(70):1211-1219. 2014. Abstract

The vigilance decrement in executive function is attenuated when individual chronotypes perform at their optimal time of day. Lara T, Madrid JA, Correa A. PLoS ONE. 9(2): e88820. doi:10.1371/journal.pone.0088820. Abstract



A comparison of B16 melanoma cells and 3T3 fibroblasts concerning cell viability and ROS production in the presence of melatonin, tested over a wide range of concetrations. Bonmatí-Carrión MA, Alvarez-Sanchez N, Hardeland R, Madrid JA, Rol de Lama MA. International Journal of Molecular Sciences. 2598(14):3901-3920. 2013. Abstract

Effects of resveratrol on changes induced by high-fat feeding on clock genes in rats. Miranda J, Portillo MP, Madrid JA, Arias N, Mcarulla MT, Garaulet M. British Journal of Nutrition. 110(8):1421-1428. 2013. Abstract

Influence of gestational diabetes on circadian rhythms of children and their association with fetal adiposity. Zorzona-Moreno M, Fuentes-Hernandez S, Prieto-Sanchez M, Blanco JE, Pagan A, Rol de Lama MA,Parrilla JJ, Madrid JA, Sanchez-Solis M, Larque E. Diabetes-Metabolism Research and Reviews. 29(6):6483-6491. 2013. Abstract

Influencia de la exposición a la luz sobre el sistema circadiano. Martinez-Nicolas A, Ortiz-Tudela E, Rol de Lama MA, Madrid JA. Vigilia-Sueño. 25(1):25-37. 2013. Abstract

Long-term social isolation in the adulthood results in CA1 shrinkage and cognitive impairment. Pereda-Perez I, Popovic N, Otalora BB, Popovic M, Madrid JA, Rol de Lama MA, Venero C. Neurobiology of Learning and Memory. 106:31-39. 2013. Abstract

Period gene expression in the brain of a dual-phasing rodent, the Octodon degus. Otalora BB, Hagenauer MH, Rol de Lama MA, Madrid JA, Lee TM. Journal of Biological Rhythms. 28(4):249-261. 2013. Abstract

Rest-activity circadian rhythms in aged Nothobranchius korthausae. The effects of melatonin. Lucas-Sánchez A, Almaida-Pagán PF, Martinez-Nicolas A, Madrid JA, Mendiola P, de Costa J. Experimental Gerontology. 48(5):507-516. 2013. Abstract

Uncovering different masking factors on wrist skin temperature rhythm in free-living subjetcs. Martinez-Nicolas A, Ortiz-Tudela E, Rol de Lama MA, Madrid JA. PLoS ONE. 8(4):e61142. 2013. Abstract

Differences in circadian rhythmicity in CLOCK 3111T/C genetic variants in moderate obese women as assessed by thermometry, actimetry and body position. Bandin C, Martinez-Nicolas A, Ordovas JM, Ros-Lucas JA, Castell P, Silvente T, Madrid JA, Garaulet M. International Journal of Obesity. 37(8)1044-1050. 2013. Abstract



Daily profile in two circadian markers “melatonin and cortisol” and associations with metabolic syndrome components. Corbalan-Tutau D, Madrid JA, Nicolas F, Garaulet M. Physiology and Behaviour. 17:231-235. 2012. Abstract

Age-related changes in mitochondrial membrane composition of rainbow trout (Oncorhynchus mykiss) hearth and brain. Almaida-Pagán PF, de Costa J, Mendiola P, Tocher DR. Comparative Biochemistry and Physiology B – Biochemistry & Molecular Biology. 163(1):129-137. 2012. Abstract

Changes in tissue and mitochondrial membrane composition during rapid growth, maturation and aging in rainbow trout, Oncorhynchus mykiss. Almaida-Pagán PF, de Costa J, Mendiola P, Tocher DR. Comparative Biochemistry and Physiology B – Biochemistry & Molecular Biology. 161(4):404-412. 2012. Abstract

Chronobiological aspects of obesity and metabolic syndrome. Gomez-Abellan P, Madrid JA, Ordovas JM, Garaulet M. Endocrinología y Nutrición. 59(1):50-61. 2012. Abstract

Circadian dysfunction in a rotenone-induced parkinsonian rodent model. Lax P, Esquiva G, Esteve-Rudd J, Otalora BB, Madrid JA, Cuenca N. Chronobiology International. 29(2):147-156. 2012. Abstract

Circadian system functionality, hippocampal oxidative stress, and spatial memory in the APPswe/PS1dE9 transgenic model of Alzheimer disease: effects of melatonin or ramelteon. Otalora BB, Popovic N, Gambini J, Popovic M, Viña J, Bonet-Costa V, Reiter RJ, Camello PJ, Rol de Lama MA, Madrid JA. Chronobiology International. 29(7):822-834. 2012. Abstract

Envejecimiento del sistema circadiano. Lucas-Sánchez A, Martínez-Nicolás M, Escames G, de Costa J. Revista Española de Geriatría y Gerontología. 47(2):76-80. 2012. Abstract

Exercise and melatonin in humans: reciprocal benefits. Escames G, Oturk G, Otalora BB, Pozo MJ, Madrid JA, Reiter  JA, Serrano E, Concepción M, Acuña-Castroviejo D. Journal of Pineal Research. 52(1):1-11. 2012. Abstract

Glucocorticoids affect 24 h clock genes expression in human adipose tissue explant cultures. Gomez-Abellan P, Diez-Noguera A, Madrid JA, Lujan JA, Ordovas JM, Garaulet M. PLoS ONE. 7(12):e50435. 2012. Abstract

La cronodisrupción como causa de envejecimiento. Ortiz-Tudela E, Bonmati-Carrion MA, de la Fuente M, Mendiola P. Revista Española de Geriatría y Gerontología. 47(4):168-173. 2012. Abstract

Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling. Hardeland R, Madrid JA, Tan DX, Reiter RJ. Journal of Pineal Research. 52(2):139-166. 2012. Abstract

Timing and duration of sleep and meals in obese and normal weight women. Association with increase blood pressure. Corbalan-Tutau MD, Madrid JA, Garaulet M. Appetite. 59(1):9-16. 2012. Abstract

When de circadian clock becomes a ticking time bomb. Reiter RJ, Tan DX, Madrid JA, Erren TC. Chronobiology International. 29(9):1286-1287. 2012. Abstract.

Wrist skin temperature, motor activity, and body position as determinants of the circadian pattern of blood pressure. Blazquez A, Martinez-Nicolas A, Salazar FJ, Rol de Lama MA, Madrid JA. Chronobiology International. 29(6):747-756. 2012. Abstract



Sexual dimorphism in clock genes expression in human adipose tissue. Gomez-Abellan P, Madrid JA, Lujan JA, Frutos MD, Gonzalez R, Martinez-Augustin O, de Medina FS, Ordovas JM, Garaulet M. Obesity Research. 22(1):105-112. 2011. Abstract

Complexity Changes in Human Wrist Temperature Circadian Rhythms through Ageing. Marin R, Campos M, Gomariz A, Lopez A, Rol MA, Madrid JA. Foundations on Natural and Artificial Computation. 6686:401-410. Abstract

Age-related brain pathology in Octodon degu: blood vessel, white matter and Alzheimer-like pathology. van Groen T, Kadish I, Popovic N, Popovic M, Caballero-Bleda M, Otalora BB, Vivanco P, Rol de Lama MA, Madrid JA. Neurobiology of Aging. 32(9):1651-1661. 2011. Abstract

Age-related changes in fatty acid profile and locomotor activity rhythms in Nothobranchius korthausae. Lucas-Sanchez A, Almaida-Pagan PF, Madrid JA, de Costa J, Mendiola P. Experimental Gerontology. 46(12):970-978. 2011. Abstract

An approximation to the temporal order in edogenous circadian rhythms of genes implicated in human adipose tissue metabolism. Garaulet M, Ordovas JM, Gomez-Abellan P, Martinez JA, Madrid JA. Journal of Cell Physiology. 226(8):2075-2080. 2011. Abstract

Assessment of circadian rhythms of both skin temperature and motor in infants during the first 6 months of life. Zorzona-Moreno M, Fuentes-Hernandez S, Sanchez-Solis M, Rol de Lama MA, Larque E, Madrid JA. Chronobiology International. 28(4)330:337. 2011. Abstract 

“Catching the spike and tracking the flow”. Holter-temperature monitoring in patients admitted in a general internal medicine ward. Varela M, Ruiz-Esteban R, Martinez-Nicolas A, Cuervo-Arango JA, Barros C, Delgado EG. The International Journal of Clinical Practice. 65(12):1283-1288. 2011. Abstract

Circadian dysfunction in P23H rhodopsin transgenic rats: effects of exogenous melatonin. Lax P, Otalora BB, Esquiva G, Rol de Lama MA, Madrid JA, Cuenca N. Journal of Pineal Research. 50(2):183-191. 2011. Abstract

Crosstalk between environmental light and internal time in humans. Martinez-Nicolas A, Ortiz-Tudela E, Madrid JA, Rol de Lama MA. Chronobiology International. 28(7):617-629. 2011. Abstract

Differences in daily rhythms of wrist temperature between obese and normal-weight women: associations with metabolic syndrome features. Corbalan-Tutau MD, Madrid JA, Ordovas JM, Smith CE, Nicolas F, Garaulet M. Chronobiology International. 28(5):425-433. 2011. Abstract

Effect of masking organoleptic properties of fat on diet self-selection by the sparid Diplodus puntazzo. Almaida-Pagan PF, Hernandez MD, Madrid JA, de Costa J, Mendiola P. Aquaculture Nutrition. 17(2):e45-e55. 2011. Abstract